I have dosed down flea meds for years and, knock on wood, have had no problems. Having several cats and dogs, this is the most economical way for me to do it. With all the cats and dogs there are in the world, HOW can flea meds be SO expensive? I recently came across this chart of dosages for several of the most common brands of flea meds and am reprinting it here for anyone else needing it.

Ask your vet for the correct dosing and medications for YOUR animal. This list is just a reference guide and is not intended to avoid veterinary guidance or advice.

Advantage required adult fleas to ingest the medication, at which point they would be impacted by the insect-specific neurotoxins and die. Advantage II kills fleas on contact, with the addition of three new chemicals to its formula, that makes your dog or cat’s skin an entirely inhospitable environment for pests. Eggs are killed before they hatch. Adult fleas are killed and will fall off, or will be washed off in your dog’s next bath.

Dog Product Insert | Cat Product Insert

**Dose is 0.05ml/pound. Multiply 0.05 times your pet’s weight for more precise dosage.**

Weight | Dosage |
---|---|

Cats/Dogs up to 9 pounds | 0.4 ml |

Cats 10+ pounds | 0.8 ml |

Dogs 11-20 pounds | 1.0 ml |

Dogs 21-30 pounds | 1.2 ml |

Dogs 31-40 pounds | 1.6 ml |

Dogs 41-50 pounds | 2.0 ml |

Dogs 51-60 pounds | 2.4 ml |

Dogs 61-70 pounds | 2.8 ml |

Dogs 71-80 pounds | 3.2 ml |

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Dog Product Info | Cat Product Info

**The dose is 0.0305ml/pound. Multiply 0.0305 times your pet’s weight for more precise dosage.**

Weight | Dosage |
---|---|

10 lbs | 0.3 ml |

15 lbs | 0.45 ml |

20 lbs | 0.6 ml |

25 lbs | 0.75 ml |

30 lbs | 0.9 ml |

40 lbs | 1.22 ml |

50 lbs | 1.5 ml |

60 lbs | 1.8 ml |

88 lbs | 2.68 ml |

90 lbs | 2.7 ml |

133 lbs | 4.0 ml |

**NOTE: If you’re using Frontline Plus —**

The amount of fipronil in the dog version is the same as in the cat version. The “Plus” is methoprene, an insect growth regulator. There’s LESS of it in the dog product than in the cat product, so it’s safe to use the dog product on the cats but **do NOT use the cat product on a small dog.**

**Generic Frontline Plus for dogs** may contain a different ingredient than the brand name. If a generic Frontline product contains something **other than methoprene or fipronil** **it may not be safe on your cat**.

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Revolution® has a single active, safe in both cat and dog, but it’s concentration varies: the formulation for puppies, kittens and cat is half strength. If splitting a large dog vial and applying the volume stated on the packaging for a cat, a double dose would be given. Take careful note of the half volumes shown below (concentration: 60mg/ml vs 120 mg/ml. Concentration amount is shown on the package.).

**(General guideline based on 120mg per 1ml potency*. ****Dose is 0.025ml/pound. Multiply 0.025 times your pet’s weight for more precise dosage.**

Weight | Dosage |
---|---|

0.0-5 lb dog/cat | 0.12 ml |

5.1-10 lb dog/cat | 0.25 ml |

10.1-20 lb dog/cat | 0.5 ml |

20.1-40 lb dog | 1.0 ml |

40.1-85 lb dog | 2.0 ml |

85.1-130 lb dog | 3.0 ml |

**(based on 60mg per 1ml potency*. Dose is 0.05ml/pound. Multiply 0.05 times your pet’s weight for more precise dosage.)**

Weight | Dosage |
---|---|

Up to 5 lb cat/dog | 0.25 ml |

5.1-15lb cat | 0.75 ml |

- Potency/concentration is noted on the packaging.

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

** *Dose is 0.045ml/pound. Multiply 0.045 times your dog’s weight for more precise dosage.**

The recommended minimum dose is 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin, once a month, by topical administration

Product Info For Dogs | Product Insert for Dogs

Dog’s Weight | Dosage | Imidacloprid | Moxidectin | Product |
---|---|---|---|---|

3-9 lbs | 0.4 ml | 40 | 10 | Advantage Multi 9 |

9.1-20 lbs | 1.0 ml | 100 | 25 | Advantage Multi 20 |

20.1-55 lbs | 2.5 ml | 250 | 62.5 | Advantage Multi 55 |

55.1-88 lbs | 4.0 ml | 400 | 100 | Advantage Multi 8 |

~~~~~~~~~~~ ~~~~~~~~~~~~ ~~~~~~~~~~~ ~~~~~~~~~~~~

***Dose is 0.045ml/lb. Multiply 0.045 times your cat’s weight for more precise dosage.**

The recommended minimum dose is 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin, once a month, by topical administration.

Product Info For Cats | Product Insert for Cats

Cat’s Weight | Dosage | Imidacloprid | Moxidectin | Product |
---|---|---|---|---|

2-5 lbs | 0.23 ml | 23 | 2.3 | Advantage Multi 5 |

5.1-9 lbs | 0.4 ml | 40 | 4 | Advantage Multi 9 |

9.1-18 lbs | 0.8 ml | 80 | 8 | Advantage Multi 18 |

*dosage is approximate. My math calculations came out to be 0.05ml/lb, but there is a discrepancy with packaged dosages. Also **there is more Moxidectin in the dog formula than in the cat formula, so I would not put the dog product on cats.**

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Weight | Dosage |
---|---|

0-10 lb dog | 0.4 ml |

11-20 lb dog | 0.8 ml |

21-30 lb dog | 1.2 ml |

31-40 lb dog | 1.6 ml |

41-50 lb dog | 2.0 ml |

51-60 lb dog | 2.4 ml |

61-70 lb dog | 2.8 ml |

71-80 lb dog | 3.2 ml |

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

**Flea Allergic pets, **like those of us allergic to mosquito bites, ** **will incessantly itch and pull out all their hair if just one flea gets past the flea control. Given most spot on agents only achieve high kill rates, above 95%, for the first 2 weeks of the month, twice monthly application is often recommended by dermatologists when treating flea allergy.

Manufacturers packaging protects the product from 2 important things: **light and air.** Drugs and insecticides can be destroyed and rendered ineffective if mishandled. Keep in the vial and store in a cool, dark place. The fridge is ideal, but under the sink or any other ‘chemical repository’ is ok. Do not freeze. You may also decide to keep the entire flea medication in the syringe itself which is fine but far from ideal. I recommend an airtight glass vial. The key point is no air exposure, no light, and no heat and they will last a very long time.

*reprinted from Starlight Boston Terriers, Global Watchdog, and others.*

So happy I found your site. We have inside rescue cats ranging 1 year-16 years old… a couple ran outside over the summer and we’ve been finding some worms when scooping the litterboxes… So treatment for everyone since they share several boxes.

Previously our vet down-dosed using Advantage Multi Dog, but now says to just use Revolution Plus Cat/weight ($230 for 1 month treatment!) According to your chart for Advantage Multi, it reads that you DO NOT recommend for cats: “Also there is more Moxidectin in the dog formula than in the cat formula, so I would not put the dog product on cats.”…. Is this still the case- that you would NOT use a down dose Advantage Multi Dog for your cats? If not, what do you use for fleas/multi-wormer/ear mites and the calcultations?

Down dose info from our vet are spot on with your calculations:

DOG-Advantage Multi for cat/ lb:

2-5 lb = .25 ml

5-9 lb = .4 ml

9-18 lb = .8 ml

Do you know of Depo Medrol/options for an elderly cat that will vomit without a monthly shot($25/shot/month)? – when I call they say ‘we’ll make up your depo allergy shot’, so I was wondering if that is something I could affordably do?

Thank you for a wonderful site of useful information to help us afford loving all the fur babies!

I am answering in no specific order, so please bear with me.

Depo Medrol is Methylprednisolone acetate, correct? So it is a more potent (and injectable) version of prednisolone. Will prednisolone work? Both medications are for reducing inflammation. I don’t understand the link to vomiting that you mention.

There is a topical flea product called Stronghold which is the same as Revolution but less expensive, in both dog and cat formulations. I buy my Stronghold from a company called Sierra Pet meds. They have several offers and sometimes throw in a free tube or two, but shop around and find the best price for you. Stronghold/Revolution handles fleas & heart worms, intestinal parasites, ear mites and worms. The largest dog size comes in a 2 ml tube, but the strength is 240 mg of selamectin so the dosage would be .0125/lb.

Advantage Multi for DOGS contains more Moxedectin than the cat version. For example, the dog formula for a 9 lb dog would be 40 IMIDACLOPRID and 10 MOXIDECTIN where the cat formula for a 9 lb cat is 40 IMIDACLOPRID and 4 MOXIDECTIN. Moxidectin is responsible for handling heartworm and intestinal worms. The ~2.5x difference is what I find concerning enough to not recommend using the dog formula on cats.

The down dosage for Advantage Multi for cat can be more weight specific by applying the math of 0.05ml/lb, so a 7 lb cat would get .35 ml rather than 4 ml. If you have a lot of cats, the difference eventually treats another whole cat. 🙂

Hope this helps.

I believe this will help a lot of people that have multiple pets that can’t afford to keep them treated without some kind of a break. Doing it this way allows a person to give their pet a better quality of life. I’m grateful for this site and all the information. Thank you

Thanks back at you.

Yes, I see Advantage and Revolution.. the med that I’ve purchased is Activyl. Thank you for your time if someone has used Activyl in dog packaging and dosed it down for cats. I was going on the info sent in response to “Tim” in July 2019.

Okay, I see what you are saying. There’s this dosing on the MSD Animal Health website: The recommended dose of Activyl for cats is 25 – 166.6 mg indoxacarb/kg bodyweight, equivalent to 0.128 – 0.85 mL/kg bodyweight. Perhaps the lower end will give you a starting point. And here is Merck’s Product Info Sheet for Activyl.

Hi, I found your site and I really appreciate. Like a lot of people, I have found that Advantage no longer works down here, and Revolution is just too far off the price spectrum. I have had good success with Activyl but never thought to buy it for XL dogs and dose it down for cats. I found this information above but that is a really big range 0.128 – 0.85 mL/kg bodyweight ..? An 8lb cat could either get 0.5ml up to 3ml. That’s a huge difference. Am I doing something wrong? Thanks!

In the paragraph above the dosing chart there is a more precise measure. For example — above the chart for Revolution, it says: Dose is 0.025ml/pound. Multiply 0.025 times your pet’s weight for more precise dosage. For Advantage, it says: Dose is 0.05ml/pound. Multiply 0.05 times your pet’s weight for more precise dosage.

You can use these more precise measures to zero in on how much to use for your companion.

Would the dosage be the same for K9 Advantix II and Advantix? My puppy is about 2.5 to 3 lbs

Yes, the difference between the two is the addition of Pyriproxyfen to Advantix II that affects mostly young insects and eggs.

Now there is Frontline ‘GOLD’ Does anyone know if the large dog dose for cats is the same as the Frontline ‘Plus’? Thank you.

I also think this is a wonderfully helpful site and thank you for helping the lady with info for her ferals that needed to be spayed/neutered!

Thanks for the heads up. Frontline states that their Gold product is safe for cats, so I would imagine it can be dosed down. We’ll see if we can find a measure and add it to the page.

I have Advecta 3 for xlarge dogs. I can’t seem to find Advecta 3 dosages on any other sites. I have a 10lb dog.

I don’t have the specifics for Advecta. There may be an insert in the product that states more specifically how much to apply per pound, but in general, the dosage is:

ADVECTA 3 DOSAGE SIZES:

5-10 Lbs= 0.4 ml

11-20 lbs= 1 ml

21-55 lbs= 2.5 ml

55 & up= 4.01 ml

So in the case of your 10 lb dog, it looks like you would use 0.4 ml.

Hi

I work in cat rescue and came here for the dosage for cats for Frontline (we normally use Advantage or Revolution).

I noticed however that either your 0.0305 multiplier is wrong or your dosage for 1-9lbs. is incorrect.

0.0305ml x 9 = 0.2745ml, which is significantly smaller than your listed 0.5ml.

Rescue groups give 0.5ml for adults cats so your 0.5ml is correct.

However the multiplier for 9lbs is 0.0555555556; 10 lbs. is 0.05

9lbs. x ? = 0.5ml

? = 0.5 / 9

? = 0.0555555556

For simplicity we can call it 0.05

To meet your listed 0.5ml for a 9lb. cat, the correct multiplier is roughly 0.05 which changes the other doses:

10lbs x 0.05ml = 0.5ml

15lbs x 0.05ml = 0.75ml

I noticed this because you listed 0.5ml for 1-9lbs, then 0.3 for 10lbs and 0.45ml for 15lbs.

Being that 0.3 and 0.45 are both smaller than 0.5, using smaller dosages on a bigger cat didn’t make sense.

Hope this helps and wasn’t confusing.

-Art

PAWSitivelySAFE

California

Thanks much for the input. I will check the numbers and make the adjustments as needed.

Update 08/07/19: We had included the dosage from the package in the original post. I think that is where the confusion came in, so we have deleted that info and restructured the tables so they are hopefully easier to read. Please let us know if you note any problems/questions.

Love the site and the calculations are spot on. However, do you have the calculations for converting Extra Large dog ACTIVYL for use on cats?

The recommended dose for cats is 25 – 166.6 mg indoxacarb/kg bodyweight, equivalent to 0.128 – 0.85 mL/kg bodyweight. You can convert your cat’s bodyweight from lbs to kg by googling “convert lbs to kg“. Here’s a chart showing the dosage breakdown for Activyl.

As a caution, the manufacturer states:

Do not use Activyl for dogs on cats, or allow your cat to lick or groom a dog treated with Activyl.This is likely a precaution so cats do not overdose on the product, so proceed with caution, especially if using this on multiple cats at one time.I just wanted to say I refer to your website again and again. Thank you for all your information. That was really nice that you helped guide the lady with the feral cat issue in Texas.

Thank you. Much appreciated.

Hello,

And 1st off: Thank you! Thank you!

I apologize if I somehow missed it…I have a 10lb cat. But the only flee meds I have are for our large dog: 62lbs. We have Frontline and Advantage Multi…how can I convert one or the other to use on my cat? And by the way after long extensive is searching for a very long time this is by far the best website I have found

Thanks for the compliment!

You will need a small oral syringe to do this. If you don’t have one, they can generally be purchased at a pharmacy or a feed store for a few cents.

For Advantage Multi, multiply 0.045 times your cat’s weight for the dose. So .045 x 10 = .45ml.

For Frontline, I have never found a measurement for plain Frontline for use in cats; just Frontline Plus which has different ingredients. So I cannot recommend that you use plain Frontline for your cat.

Thank you, so much for this!

After reading your helpful information, in order to obtain the greatest savings, we would purchase the 6 pack Advantage Multi for the largest dogs. After doing the math for the exact dosage on our 12 pound dog, this 6 pack purchase would last us a little over 32 months.

Can you advise if there is an expiration date on the individual 6 packs of Advantage Multi?

I believe the expiration date is on the box only. I have some Advantage here (not the Multi), but I do not see an expiration date on the individual tubes.

Activyl (FLEA ONLY) formulation can definitely be used on cats, we have done so and our vet told us it was the same. Yes, from the usa, SierraPetMeds is a great resource and accept Paypal.

I am on a fixed income and had a recent stroke. Recently blessed with about 25 feral cats many of them young and pregnant. No idea how they found me as I live about 10 miles out in the Texas country side but here we are. I have 6 cats and 3 dogs of my own and this information is so very helpful. The county I live in offers no affordable spay/neuter programs and I can no longer drive so I just keep feeding the masses and again, here we are. I am originally from Michigan and am missing the kill season on fleas so very much. Thanks again.

I’m not sure where you are located but there is an clinic in Brenham called Animal Friends of Washington County that works with a lot of the area rescue groups. Give them a call and explain your situation. Maybe they can hook you up with some rescue groups that could help you because those babies will just keep multiplying and you will get overwhelmed.

Here’s their phone number: (979) 277-0400

Thank you for this post,

As a multiple cat owner this is extremely important information to have,

I have to say thought, that recently, it seams that the usual flea med I have been using (namely Advantage and Revolution) does not work in eliminating my cats flea problem 🙁

I was wondering if you have any information about the Bravecto’s solution efficiency, can I dose it down (I think it has the same active ingredients in the same concentrations), and how much should I use on my cats.

Thank you!

It seems to me that most flea meds last 3 weeks, not 4 at my house. I have not worked with Bravecto. It concerns me that something you apply topically (or even through an edible) would last for 12 weeks. What must those first weeks when the drug is most potent involve? So I generally steer clear of it. There is a product called Stronghold which is the same as Revolution, but cheaper.

Sierra Pet Meds sells a supply kit for cats and dogs that is generally a bit cheaper, too.

I use a company called Pets megastore. They are in located in Australia. Great prices and I get Revolution from them all the time. I worked for 7 years at a veterinary office. I learned a lot from the reps. that sold us our flea control. Learned how to break it down to save money. I have also been in rescue for years. I have learned different ways of saving money on meds and flea control. I use to do all the drug ordering for our vet. office. Pets mega sells Virbac tapeworm pills my vet used. They are in kilograms. 1-pill does a 22lb. dog or cat. I use 1/2 pill for an 11-pound cat, 1/4 pill for 5.5 lb. cat. You get the idea. Saves a lot of money. Please check their site. I live in Calif. and have used them for over 10-yrs. I have never had any problems and receive my order in 7-days. I hope this information helps.??

GREAT info. Thank you.

hello Isak, Thank you for this valuable website.

I’ve been told by a farmer that I can use the product Thiraflo active ingredient is Thiram. It is a fungicide that’s used to spray seeds. He said it’s the same as Fipronil, the active ingredient in flea treatments.

Is any of the information he gave me correct. Have you heard of this Thiram chemical being used on animals.

Is it safe to do so. Thanks so much for your help

Tanya

Thiram is a fungicide; Fipronil is an insecticide. I don’t see that they are the same thing at all. I would not recommend Thiram.

great reference.

my favorite flea killer is comfortis. no worries about seperating them or licking it off themselves or each other. cats may not be able to lick the back of their own head, but my cats help each other with the hard to lick areas.

so i do the same thing with comfortis (for xl dogs) & a digital postal scale (it needs to weigh to hundredth, meaning it has to have 2 numbers after the decimal point). the dosage for dogs is .13 & cats is .22, but i dose mine at .1 for dog & .18 for cats. ive tried the higher dose, but it still doesnt last 4 weeks & causes lethargy & upset tummies. so i give the lower dose about every 3 weeks. i crush up the giant pill & dose all the ones who will let me weigh em by their exact weight, like a 10 lb cat get 0.18 on scale. 5lb gets 0.09

7lb comes out to .126 on calculator so i round it to 0.13

i guess for the ones who wont let me pick em up & i try to guess on the high side. they’re still getting less than if i bought expensive individual doses for each cat, where they have u give a 5 lb cat & 10 lb cat the same dose!

i make em wait a few hours past mealtime so i know theyre really hungry. i massage the appropriate amount of powder into the pillpocket (so there aren’t any pieces to spit out) & i top with the littlest bit of wet food, like 1/4 teaspoon, so they eat it all in one bite & no one accidentally eats extra doses.

after everyones dosed they get canned food (with a lil olive oil added) as much as they want cause it works better with a belly full of a fatty meal. i keep an eye on em for an hour cause if they barf they need another dose or a topical to kill the fleas.

i order my comfortis xl online, from a country where an rx isn’t needed

Thank you for this site!

Thank you for creating this site. Im on a fixed income and have used a single frontline for large dogs on my 2 medium sized dogs and my 8 cats each month of flea season for several years. I measure carefully and my very effective flea treatment cost me under 20 dollars a month. This is a great way to get this info out there so multi pet families with a low income can keep their fur babies comfortable throughout flea season.

What is the best flea prevention that last the longest. Need safe for kittens.

And do Fleas have to bite to work.

The “best” is probably a personal choice. My personal choice is Revolution. It is effective in keeping cats safe from adult fleas, flea eggs, flea larvae, as well as heartworm, intestinal worms and other nasties. Revolution is approved for use with kittens and puppies as young as 6 weeks old, as well as pregnant and lactating females.

That said, it seems that most of the flea meds I have tried start to wear off after three weeks, not the four they promise, but I also dose based on weight and not the general weight class of the med.

Just be sure that when using any of these products on cats or kittens that you apply it as directed so they cannot lick it or otherwise get it in their mouth (like paw the area where the meds are and lick their paws). You want to apply it onto the skin just in front of your cat’s shoulder blades.

I was told by a vet to always stay away (far away) of anything ending in ‘thrin, she called them “the thrins”. This warning to stay away is for cats, and as you said “permeTHRIN” is a baddy. Thanks to you and all the compassionate vets out there who know how ridiculously and unnecessarily expensive this stuff is,and do what they can to help people make safe choices for their furry friends! Hate those bloodsuckers.

Hi !i wanted to ask Debra if she did in fact use the termite “ medication?” And if everything worked out fine as I somehow adopted three stray females and before I could fix (of course this is certainly fun for my daughter and I?) all three have had Kittens!! ? so we currently have seventeen kitties! Of course only two litters are over the dosing ages but I would like to do it before I give them away. So was just wanting to know.

In addition, now do you think between my nine year old daughter and I loving all these – that all aeventeen will be leaving?? Ha! ? I don’t believe I will need to answer that! (Omg I picked more than her!) lol Okay thanks! Bye bye! 🙂

So most Fipronil products have methoprene ….. if you find it can you use straight Fipronil 9.1% at these same dosages? Most termite control insecticide is Fipronil 9.1% like Taurus SC in its concentrated form…. I bought a 20 oz bottle to treat the yard when I realized this is the SAME minus the methoprene. For anyone with 20+ cats this can be a $$ saver. 20 oz was $43. Wat would be your take on it?

I don’t have a good answer for you. One concern would be the effects of applying this product directly to the skin as these are serious chemicals. I would do more research before giving this a try as complications may not appear immediately after dosing. Personally, I buy large dose dog flea meds and dose them down.

Here is some scary info about flea meds in general. Though it is several years old, I think it may still be relevant today.

I’m sorry may be a little confused. I have just ordered Revolution for extra large dog 3 pack. I want to break it up in doses for my 22 pound dog. What is the dose I would give her?? Thanks a lot

Ann

It can be confusing, but the formula is pretty simple. The potency in the dog versions is 120 mg/tube in all but the smallest (puppy) tubes. If they didn’t reduce the potency in the smallest version, the product would be all tube and very little flea solution. You say you bought the extra large dog pack and your dog is 22 lbs. so what you want to do is multiply your dog’s weight by 0.025 to get your dose.

22 x .025 = 0.55 mlIf you go a bit above this amount, it will not hurt.

To verify this amount, look at the box for a 10.2-20 lb dog. The amount in each tube is 0.50 ml. Your dog is slightly heavier so your dose is slightly higher: 0.55 ml.

Hope that helps.

Wow – This is such a work of love. Thank you so much. I have yet to totally figure everything out, but the concept of reducing the amount of flea medication is really important to me given the reactions and deaths that occur from some of these mediations. Thank you again.

What are your concerns and thoughts regarding Fluralaner (Bravecto) for dogs?

I don’t have any experience with Bravecto. Though it is touted as a 12-week solution for fleas and ticks, it seems that for the Lone Star tick, they recommend redosing every 8 weeks. You can read this endorsement from a vet in Canada. A “Freedom of Information Summary” [PDF] dated 15 May 2014 is available on the Food and Drug Administration’s (FDA) web site. It’s an interesting read. From it, there is this:

So just be aware of the side effects you might encounter. And if you try it, let us know what you think. I’d love to share your experience with our readers.

I wanted to say thank you so much for all the information that is provided here. It has been such a help in figuring out dosage amounts of flea treatments for our animals. Like many people who visit this site, we take in strays, we try to get them spayed and nuetured but cant seem to ever get them all fixed in time. Our “colony” is at 60+ cats and kittens right now, not to mention the 6 dogs we have as well. The flea meds we were using stopped working and have recently switch brands to advantage 2 for the cats and a generic brand called pet defender+ for the dogs. However we ran out of the advantage before all the cats were dropped. There are about 12 who have not been treated. Is it ok to drop the remaining cats with the drops that are for the dogs? Any help would be greatly appreciated. We are beyond overwhelmed.

Wow, 60+. You have me beat.

I am not familiar with Pet Defender+, but in general, if they make a cat version, compare the ingredients to the dog version. If they are the same, you should be okay.

If the product contains permethrin, DO NOT use it on the cats.While dogs can metabolize permethrin effectively, resulting in a safe product for them, cats cannot metabolize this ingredient and will suffer from toxic effects if exposed.I have a question. Sorry if it’s listed somewhere. I have multi-dosed our pets before. I use Frontline Plus. Anyway, I think I bought the extra large dog size and dosed it out from there. I can’t remember since it’s been awhile since I needed to buy new. Do it need to get the extra large for the doses to be correct? Thank you.

The dosage is based on the weight of your pets. The extra large will generally cost you less per dose than the smaller sizes and you will get more doses out of the tube. However, if you open a tube and do not use it all, you need to close it tightly and keep it out of the light.

Bless you for all you do. REALLY appreciate this website. I’ve had to switch to Activyl as the Advantages 1 & 2 don’t work anymore, and I can’t buy Revolution w/Paypal in America, not for a decent price, anyway.

Like everyone else, I rid many rescues and several colonies of fleas, and doing 20+ cats on a fixed income…it has to be as cheap as possible.

Have you tried Activyl – fleas ONLY for X-large dogs…on cats? I’d love to get a lowdown on the dosages. Thank you!

Bless you for all you do. We’ve been rescuing cats off our streets for 15 years. I’m a bottle mom. Love it!

Thank you for your kind words. And bless you for all you do. I live in the country and somehow, stray cats seem to migrate to my yard despite having dogs (who love cats because they have always lived with cats), so I understand what you are saying. Advantage seems to work for me, but only for 3 weeks max. I’ve read where other people have reported that, too.

I don’t know much about Activyl, but if the quantity of the active ingredient is the same in both products (for example: 19.53% Indoxacarb in both products), then there is a good chance that the non-tick version can be dosed down for cats. That’s generally the qualifier — same product, same ingredients, different packaging. So based on what the dosages are showing for the different products, you can determine how to dose your cats. Maybe the dosing amount will follow something similar to others we are showing on this post and that will help you micro-tune your dosages.

Have you tried Sierra Pet Meds for your flea medications? I think they might take PayPal. They generally have good prices and they have a rewards program. I have used them often.

Let me know what you do and how it works. You aren’t by chance in or near Raleigh, NC, are you? If so, there is a woman with some health/mobility issues who is looking for help with her colony. Any suggestions would be appreciated.

I am so very grateful to you for providing this information! We have 5 cats and 2 dogs (all rescues), and I have often been riddled with guilt when funds have been too tight for flea meds (which seems to be too often). All 9 of us (my hubby and self included) THANK YOU, THANK YOU, THANK YOU!!!!!!!!!

Thanks so much…I am broke, on a fixed income but I am going to try and donate thru PayPal link provided.

Thanks much for the kind gesture, but don’t send a donation if you need it for you and your companions.

Thanks for posting this! I have been using half-doses of the anti-flea products for years and I have never had a single problem. Here in Michigan, I completely stop dosing around November – March (in my dog-loving neighborhood, I recently discovered that most dog parents are doing the same thing) . The doses given full strength as indicated on the package inserts, when I have tried them, have always made my pets ill for a couple of days after I apply the med. The half-dose works just fine with far less side effects. I wonder if, by poisoning the fleas, we aren’t poisoning the animal at the same time.

I do get all of the recommended vaccines, though.

Thank you so much for listing all of the dosages for those different products. I’ve been doing the same thing for over 17 years now. I was taught by a wonderful – and spunky!! – little rescue lady ? But I still always like to doublecheck the dosage sizes when I switch products – I don’t want to use too much. The dosages for Advantage and Advantage II are the same, right? I am inquiring for my darling 2 yr old border collie / fox terrier mix named Dodger who weighs 49 pounds, which puts him in the large dog category. Thank You!!

P. S. I should have mentioned that I have both products on hand. Dodger seems to have a mild allergy to fleas so I wanted to use a Advantage II on him based on what you wrote. While I mentioned him, I do have cats as well so it would be handy to confirm that their dosages with the Advantage II is also the same as the regular Advantage ?

Yes, the dosage is the same for Advantage and Advantage II. The difference between the products is this: Advantage required adult fleas to ingest the medication, at which point they would be impacted by the insect-specific neurotoxins and die. Advantage II kills fleas on contact, with the addition of three new chemicals to its formula, that makes your dog or cat’s skin an entirely inhospitable environment for pests. Eggs are killed before they hatch. Adult fleas are killed and will fall off, or will be washed off in your dog’s next bath.

However be sure you do not use K9 Advantix or Advantix on your cats. It’s a dogs only formula.

Check Dr. Foster & Smith for cheaper multi. They have a sale on this product now.

Do you have a link for the Foster & Smith sale item?

Thank you you so much for this info. We live on a farm and have 6 dogs ranging in size from 6 to 95 pounds. I had already.been splitting dosage vials between 2 dogs when appropriate. So recently I thought, why not try to let the product and our money go further by finding out the dose per pound that would be effective. This article was amazing in giving info on all of these products. It was also helpful to find out the important storage info. I wish that more people could be made aware of this info. It seems like it will be good for our pets to have only the necessary amount of insecticide as well. Thanks again for this very informative article.